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现代生物技术、生物工艺学


个人简介

陈勇,全讯白菜策略研究员,国家生化工程技术研究中心副主任。本科毕业于999全讯白菜网生物工程专业,博士毕业于999全讯白菜网生物化工专业,2011年起就职于999全讯白菜网国家生化工程技术研究中心。任现职以来,主要进行微生物与吸附介质相互作用机制的研究及产业化应用。作为负责人承担了国家科技支撑计划、国家重点研发计划课题、自然科学基金面上等多项国家级项目,承担了百万级以上企业横向项目3项。在METAB ENG等高水平SCI期刊上发表论文34篇,申请专利117项,授权专利52项,其中PCT专利授权9项。荣获国家技术发明二等奖在内多项国家和省部级科技奖励。并获得了百千万人才工程国家级人选、江苏省杰出青年、江苏省青年科技奖等人才称号。


代表性成果

1. Liu D, Chen Y, Ding F, et al. Simultaneous production of butanol and acetoin by metabolically engineered Clostridium acetobutylicum[J]. Metabolic engineering, 2015, 27: 107-114.共一

2. Sun W, Yu Y, Chen J, et al. Light Signaling Regulates Aspergillus niger Biofilm Formation by Affecting Melanin and Extracellular Polysaccharide Biosynthesis[J]. Mbio, 2021, 12(1). 通讯

3. Shi X, Chen Y, Ren H, et al. Economically enhanced succinic acid fermentation from cassava bagasse hydrolysate using Corynebacterium glutamicum immobilized in porous polyurethane filler[J]. Bioresource technology, 2014, 174: 190-197. 共一

4. Liu Q, Zhao N, Zou Y, et al. Feasibility of ethanol production from expired rice by surface immobilization technology in a new type of packed bed pilot reactor[J]. Renewable Energy, 2020, 149: 321-328. 通讯

5. Liu L, Yu B, Sun W, et al. Calcineurin signaling pathway influences Aspergillus niger biofilm formation by affecting hydrophobicity and cell wall integrity[J]. Biotechnology for Biofuels, 2020, 13(1): 1-13. 通讯

6. Yang L, Zheng C, Chen Y, et al. Nitric oxide increases biofilm formation in Saccharomyces cerevisiae by activating the transcriptional factor Mac1p and thereby regulating the transmembrane protein Ctr1[J]. Biotechnology for biofuels, 2019, 12(1): 30. 通讯

7. Liang C, Ding S, Sun W, et al. Biofilm-based fermentation: a novel immobilisation strategy for Saccharomyces cerevisiae cell cycle progression during ethanol production[J]. Applied Microbiology and Biotechnology, 2020, 104(17): 7495-7505. 通讯

8. Yu B, Cheng H, Zhuang W, et al. Stability and repeatability improvement of horseradish peroxidase by immobilization on amino-functionalized bacterial cellulose[J]. Process biochemistry, 2019, 79: 40-48. 通讯

9. Chen T, Liu N, Ren P, et al. Efficient biofilm-based fermentation strategies for L-threonine production by Escherichia coli[J]. Frontiers in microbiology, 2019, 10: 1773. 通讯

10. Liu Q, Zhao N, Zou Y, et al. Feasibility study on long-term continuous ethanol production from cassava supernatant by immobilized yeast cells in packed bed reactor[J]. Journal of microbiology and biotechnology, 2019. 通讯

11. Li Z, Chen Y, Liu D, et al. Involvement of glycolysis/gluconeogenesis and signaling regulatory pathways in Saccharomyces cerevisiae biofilms during fermentation[J]. Frontiers in microbiology, 2015, 6: 139. 共一

12. Yu B, Zhang X, Sun W, et al. Continuous citric acid production in repeated-fed batch fermentation by Aspergillus niger immobilized on a new porous foam[J]. Journal of biotechnology, 2018, 276: 1-9. 通讯

13. Zhao N, Ren H, Li Z, et al. Enhancement of nuclease P1 production by Penicillium citrinum YL104 immobilized on activated carbon filter sponge[J]. Applied microbiology and biotechnology, 2015, 99(3): 1145-1153. 通讯

14. Liu Q, Cheng H, Wu J, et al. Long-term production of fuel ethanol by immobilized yeast in repeated-batch simultaneous saccharification and fermentation of cassava[J]. Energy & Fuels, 2015, 29(1): 185-190. 通讯

15. Yang L, Zheng C, Chen Y, et al. FLO genes family and transcription factor MIG1 regulate Saccharomyces cerevisiae biofilm formation during immobilized fermentation[J]. Frontiers in microbiology, 2018, 9: 1860. 通讯