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教师信息

主讲课程

《系统生物学与合成生物学》、《基因工程药物》和《酶工程》


个人简介

张阿磊,男,1993年,副教授,硕士生导师,生物化工博士,师从欧阳平凯院士。主要研究方向为以酶催化技术转化低值含氮大分子(甲壳素、硝化纤维素等)合成高值含氮化学品如材料单体、功能糖等,涉及酶挖掘、酶改造及酶催化过程强化等技术。以第一/通讯作者在生物化工领域权威期刊Green ChemistryChemical Engineering JournalCarbohydrate Polymers Biotechnology For Biofuels等发表SCI论文30余篇,中国发明专利授权8件。

个人经历

1.2013-092015-12,999全讯白菜网,生物化工,博士(导师欧阳平凯院士)

2.2018-072020-12,999全讯白菜网,博士后(合作导师陈可泉教授)

3.2021-03至今,999全讯白菜网,全讯白菜策略,副教授


代表性成果

指导学生获奖

指导本科生全国大学生生命科学创新创业大赛国家三等奖,获指导教师三等奖。

指导互联网+”创新创业大赛江苏省三等奖和校级二等奖。

指导本科生校级大创项目6项。

指导研究生获得校级奖学金3人次。


代表性项目:

近五年主持国家自然科学面上基金、国家自然科学青年基金、国家重点研发计划合成生物学专项子课题、江苏省农科院自主创新资金、中国博士后特别资助和面上(一等)等8项国家和省部级课题。


代表性论文:

1. Zhang Alei*, et.al. Self-sufficient biocatalysts constructed using chitin-based microspheres. Chemical Engineering Journal, 2023, Accepted.

2. Zhang Alei, et al. Efficient enzymatic hydrolysis of chitin into N-acetyl glucosamine using alkali as a recyclable pretreatment reagent. Green Chemistry, 2021-05-01, 23:8, 3081-3089.

3. Zhang Alei*, et.al. Chitin biopolymer mediates self-sufficient biocatalyst of pyridoxal 5'-phosphate and L-lysine decarboxylase. Chemical Engineering Journal, 2021, 427.

4. Zhang, Alei, et al. Enzymatic hydrolysis of chitin pretreated by bacterial fermentation to obtain pure N-acetyl-D-glucosamine. Green Chemistry. 2018, 20 (10): 2320-2327.

5. Zhang Alei, et.al. An efficient enzymatic production of N-acetyl-D-glucosamine from crude chitin powders. Green Chemistry. 2016, 18 (7): 2147-2154.

6.Wei, Guoguang#; Zhang, Alei#, et al. Enzymatic production of N-acetyl-D-glucosamine from crayfish shell wastes pretreated via high pressure homogenization. Carbohydrate Polymers. 2017, 171: 236-241.

7. Zhang, Alei, et al. Molecular characterization of a novel chitinase CmChi1 from Chitinolyticbacter meiyuanensis SYBCH1 and its use in NacetylDglucosamine production. Biotechnology for biofuels. 2018, 11:79.

8. Zhang, Alei, et al. A novel bacterial beta-N-acetyl glucosaminidase from Chitinolyticbacter meiyuanensis possessing transglycosylation and reverse hydrolysis activities. Biotechnology for Biofuels, 2020, 13:1.

9. Zhang, Alei, Mo, Xiaofang, Zhou, Ning, et al. Identification of Chitinolytic Enzymes in Chitinolyticbacter meiyuanensis and Mechanism of Efficiently Hydrolyzing Chitin to N-Acetyl Glucosamine. Frontier in Microbiology. 2020, 11 572053.

10. Zhang Alei*, et al. Effect of organic solvents treatment on structure of chitin and its enzymatic hydrolysis. Polymer Degradation and Stability, 2022, 198.