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主讲课程

生物分离工程、仪器分析


个人简介

杨朋朋,男,1988年,教授,硕士生导师。2016年毕业于999全讯白菜网应汉杰院士门下,生物化工专业博士,化学工程与技术、材料科学与工程方向博士后,现在应汉杰院士团队。兼任国家生化工程技术研究中心主任助理、郑州大学“生物+”联合研究中心研究生导师、南京高新工大生物技术研究院技术顾问。


代表性成果

研究方向及主要科研成果:

1)生化产品与化学品的分离精制、药物结晶;

2)生物制造的工程化应用。

5年于Chem. Eng. J.ACS Sustainable Chemistry & Engineering IUCRJUltrason SonochemJournal of Chromatography AFood Chem.IECRCrystEngComm等工程应用领域权威杂志发表论文20余篇,申请专利50余项,已获授权发明专利20余项。主持绿色生物制造国家重点研发计划课题、子课题、国家自然科学基金面上项目、青年项目等纵向横向项目10余项。获知识产权突出贡献奖、2021年江苏省教学成果二等奖


代表性论文:

1. Tao Shen, Bo Zhang, Yingying Wang, Pengpeng Yang*, Ming Li, Ruijia Hu, Kai Guo, Kequan Chen, Ning Zhu, Liang Wang, Chenjie Zhu*, Hanjie Ying. Production of 100% bio-based semi-aromatic nylon by aerobic oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid with bio aliphatic diamine, Chemical Engineering Journal, 2022, Volume 437, Part 1, 135361.

2. Pengpeng Yang, Xiaojie Li, Zihan Li, Xincao Fang, Keke Zhang*, Wei Zhuang, Jinglan Wu, Chenjie Zhu, Hanjie Ying. Green mechanochemical strategy for the construction of a new bio-based nylon 524T ternary salt, ACS Sustainable Chemistry & Engineering, v 10, n 11, p 3513-3520, March 21, 2022 .

3. Wei Zhuang, Zhenfu Wang,Wenfeng Zhou, Pengpeng Yang*, Lei Ge, Byron Villacorta Hernandez, Jinglan Wu, Ming Li, Chenjie Zhu, Hanjie Ying*, Interfacial microenvironment for lipase immobilization: Regulating the heterogeneity of graphene oxide, Chemical Engineering Journal, 2022, Volume 394, 125038.

4. Pengpeng Yang, Qingqing Li, Sen Wang; Wei Zhuang, Jingwei Zhou, Sha Zhu, Jinglan Wu*, Hanjie Ying*. Application of a humidity-mediated method to remove residual solvent from crystal lattice. Food Chemistry, 2019, 294, 123-129.

5. Zhao, Jingjing#Yang, Pengpeng#Fu, JinqiuWang, YingyingWang, ChiyiHou, YihangShi, YuzhongZhang, Keke*Zhuang, WeiYing, Hanjie. Polymorph control by designed ultrasound application strategy: The role of molecular self-assembly, ULTRASONICS SONOCHEMISTRY, 2022(89):106118.

6. Pengfei Jiao*, Xin Zhang, Na Li, Yuping Wei, Peng Wang, Pengpeng Yang*, Cooperative adsorption of L-tryptophan and sodium ion on a hyper-cross-linked resin: Experimental studies and mathematical modeling, Journal of Chromatography A, 2021, 1648, 462211.

7. Zihan Li, Shushu Li, Pengpeng Yang*, Xincao Fang, Qingshi Wen, Ming Li, Wei Zhuang, Jinglan Wu and Hanjie Ying. 
The effect of polymorphism on polymer properties: Crystal structure, stability, and polymerization of a short-chain 
bio-based nylon 52 monomer 1,5-pentanediamine-oxalate, IUCRJ,2022.

8. Pengpeng Yang, Chenguang Lin, Wei Zhuang, Qingshi Wen, Fengxia Zou, Jingwei Zhou, Jinglan Wu, Hanjie Ying*. Insight into a direct solid-solid transformation: a potential approach for the removal of residual solvents. CrystEngComm, 2016, 18 (10), 1699-1704.

9. Yang, Pengpeng; Wen, Qingshi;Wu, Jinglan; Zhuang, Wei; Zhang, Yuehui; Ying, Hanjie. Determination of Solubility of cAMPNa in Water plus (Ethanol, Methanol, and Acetone) within 293.15-313.15 K [J]. Industrial & Engineering Chemistry Research, 2014, 53 (26), 10803-10809.

10. Haodong Liu, Pengpeng Yang*, Zihan Li, Qingshi Wen, Xiaojie Li, Chenjie Zhu, Pengfei Jiao, Wei Zhuang, Jinglan Wu, Hanjie Ying. Thermodynamics, Characterization, and Polymorphic Transformation of 1,5-Pentanediamine Carbonate. Industrial & Engineering Chemistry Research, 2020, 59, (21), 10185-10194.

11. Pengpeng Yang, Xiaoqiang Peng, Sen Wang, Dong Li, Ming Li, Pengfei Jiao, Wei Zhuang,  Jinglan Wu, Qingshi Wen*, Hanjie Ying*. Crystal structure, thermodynamics, and crystallization of bio-based polyamide 56 salt. Crystengcomm, 2020, 22, (18), 3234-3241.

12. Pengpeng Yang, Junyang Jin, Qingshi Wen, Chenguang Lin, JinQiu Fu, Wei Zhuang, Jinglan Wu , Dong Liu*, Chenjie Zhu*, and Hanjie Ying. Hydrates of Adenosine 3’,5’-Cyclic Monophosphate Sodium and Their Transformation, Crystengcomm, 2021, 23 (1): 174-184.

13. Huifang Zhang†,Pengpeng Yang†,Zhenyu Wang,Mengting Li,Jie Zhang, Dong Liu*,Yong Chen* and Hanjie Ying, Clostridium acetobutylicum Biofilm: Advances in Understanding the Basis, Frontiers in Bioengineering and Biotechnology, 2021(9), 658568.

14. Zihan Li, Pengpeng Yang*, Handong Liu, Jun Liu, Sha Zhu, Xiaojie Li, Wei Zhuang, Jinglan Wu, Hanjie Ying. Crystal forms and phase transformation of 1,5-pentanediamine-terepnthalate: a bio-based nylon 5T monomer. Acta Crystallographica Section B-Structural Science Crystal Engineering and Materials, 2020, 76, 524-533.

15. 乔长晟杨朋朋*赵男, 基于代谢途径分析的多杀菌素高产菌株选育,《湖北农业科学》, 2013, 52(10):2309-2314.


代表性专利:

1. 杨朋朋,应汉杰,李子涵等;戊二胺癸二酸盐及其晶体,专利号:ZL201810335906.7

2. 杨朋朋,应汉杰,林晨光等;一种二丁酰环磷腺苷钙盐的晶体,2018.7.16,中国,专利号:ZL 201810782011.8

3. 杨朋朋;李晓洁;应汉杰等;戊二胺制备过程中含硫酸钙固渣的处理方法,专利号ZL201910278349.4

4. 杨朋朋,林晨光,温庆仕等,5’-尿苷单磷酸晶体 制备方法,专利号ZL202010999891.1

5. 应汉杰;杨朋朋;王森;吴菁岚;朱晨杰;许晟;陈可泉;陈勇;欧阳平凯戊二胺己二酸盐及其晶体 PCT /CN2018/082438

6. 应汉杰;杨朋朋;黎青青等;一种核苷酸混合物晶体粉末及其制备方法,专利号 ZL201710980961.7

7. 应汉杰,杨朋朋,温庆仕等;一种从含有戊二胺的固相中汽提回收戊二胺的方法,ZL 2019106923234

8. 应汉杰,杨朋朋,沈涛等;一种从含有戊二胺的水相中汽提回收戊二胺的方法,ZL201910692260.2;

9. 应汉杰,李子涵,杨朋朋等;戊二胺丁二酸盐及其晶体, ZL201811201323.1

10. 应汉杰;李晓洁;杨朋朋; 一种戊二胺丁二酸对苯二甲酸共晶盐及其制备方法,ZL201911365842.6

11. 乔长晟 ; 杨朋朋 ; 赵男 ; 蔡恒.  产多杀菌素刺糖多孢菌及其培养和应用,专利号:ZL201110429550.1

12. 乔长晟; 杨朋朋 ; 李栋 ; 蒋磊 ; 赵男. 一种利用活性污泥生产燃料乙醇的方法,授权公告号:CN102321723B,专利号:ZL201110207807.9


代表性项目:

1. 杨朋朋,生物制造关键共性技术开发与减碳,绿色生物制造国家重点研发计划课题,2022YFC2105402, 2022.11.1- 2026.10.312050万,主持,在研;

2. 杨朋朋,基于共结晶三元盐的生物基耐高温共聚酰胺链段结构调控新策略,国家自然科学基金面上项目,22278217, 2023.01- 2026.1254万,主持,在研;

3. 杨朋朋,国家自然科学基金-青年基金,环磷酸腺苷钠结晶水的形成机制与调控,2190810023万,2020.1-2022.12,主持,在研;

4. 杨朋朋,低廉生物质制备全生物基可降解包装材料关键技术,绿色生物制造国家重点研发计划子课题,SQ2022YFC2100472023.01-2026.1272万,主持,在研;

杨朋朋,江苏高校协同创新计划(先进生物制造协同创新中心)面上项目,XTD2207,虫草素与谷胱甘肽的高端化精制与产业应用,20万元,2021.1-2024.12,主持,在研;